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Medication - Sterile Compounding - Low Volume Hazardous Medication Preparation

Our Organization compounds a small quantity of hazardous medications. Are there any special requirements we should follow ?

Any examples are for illustrative purposes only.

Ideally, hazardous medications would be compounded in a negative pressure environment.  Currently, according to USP 797, if an organization prepares a low volume of hazardous drugs, the use of two tiers of containment is acceptable in a non-negative pressure area.   An example of 2-tier containment would be the use of a closed system transfer device utilized within a biological safety cabinet or compounding aseptic containment isolator. 
Last updated on May 11, 2020
Manual: Hospital and Hospital Clinics
Chapter: Medication Management MM

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